Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies.

@article{Fradet1984CellSA,
  title={Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies.},
  author={Yves Fradet and Carlos Cordon-Cardo and Tom Thomson and Martina E. Daly and Willet F. Whitmore and Kenneth O. Lloyd and Myron R. Melamed and L. John Old},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1984},
  volume={81 1},
  pages={224-8}
}
Mouse monoclonal antibodies were obtained by immunization with cultured human bladder cancer or lysates of bladder papilloma. They identify 11 distinct antigenic systems as defined by serological analysis of cultured cells and studies of antigen distribution in normal and neoplastic tissues. The most restricted of these antigens, Om5, defines a subset of bladder tumors. Om5 is not detected in normal bladder urothelium or in any other normal or malignant tissue. T101 and JP165 are also subset… CONTINUE READING

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