Cell surface accessibility of individual gangliosides in malignant melanoma cells to antibodies is influenced by the total ganglioside composition of the cells.

@article{Lloyd1992CellSA,
  title={Cell surface accessibility of individual gangliosides in malignant melanoma cells to antibodies is influenced by the total ganglioside composition of the cells.},
  author={Kenneth O. Lloyd and Claudia M. Gordon and I J Thampoe and C DiBenedetto},
  journal={Cancer research},
  year={1992},
  volume={52 18},
  pages={4948-53}
}
The reactivity of a panel of antiganglioside monoclonal antibodies with a number of melanoma cell lines having different ganglioside composition profiles was studied. One cell line synthesized only GM3, one produced both GM3 and GD2, 2 had GM3 and GD3 as their major gangliosides, and 2 others synthesized approximately equal amounts of GM3, GM2, GD3, and GD2… CONTINUE READING