Cell - specific differences in 06 - alkylguanine DNA repair activity during continuous exposure to carcinogen ( carcinogenesis / mutagenesis /

  • ANTHONY E. PEGGt
  • Published 2003

Abstract

The activity of the alkyl acceptor protein (AAP) responsible for repair of DNA containing the promutagenic lesion 06-alkylguanine was determined in hepatocytes and nonparenchymal cells (NPC) obtained from livers of control rats and rats exposed to hepatocarcinogens that primarily induce vascular or hepatocellular neoplasms. Basal levels ofAAP activity were… (More)

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