Cell size control - a mechanism for maintaining fitness and function.

@article{Miettinen2017CellSC,
  title={Cell size control - a mechanism for maintaining fitness and function.},
  author={Teemu P. Miettinen and Matias J. Caldez and Philipp Kaldis and Mikael Bj{\"o}rklund},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2017},
  volume={39 9}
}
The maintenance of cell size homeostasis has been studied for years in different cellular systems. With the focus on 'what regulates cell size', the question 'why cell size needs to be maintained' has been largely overlooked. Recent evidence indicates that animal cells exhibit nonlinear cell size dependent growth rates and mitochondrial metabolism, which are maximal in intermediate sized cells within each cell population. Increases in intracellular distances and changes in the relative cell… CONTINUE READING