Cell signaling arising from nanotopography: implications for nanomedical devices.

  title={Cell signaling arising from nanotopography: implications for nanomedical devices.},
  author={Adam S. G. Curtis and Matthew J. Dalby and Nikolaj Gadegaard},
  volume={1 1},
This review discusses the roles in signaling to cells by nanochemical, nanostructural (nanotopography) and mechanical means, as well as recent work and trends in nanobioscience that are relevant to therapeutic applications. It is suggested that the mechanical results may often integrate the other two types of signal. Although the field is still in an almost embryonic but rapidly developing state, it is possible to envisage potential medical devices. Nanoparticle-based therapies are recognized… CONTINUE READING

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