Cell shape and growth regulation in skeletal muscle: exogenous versus endogenous factors.

@article{Vandenburgh1983CellSA,
  title={Cell shape and growth regulation in skeletal muscle: exogenous versus endogenous factors.},
  author={Herman H. Vandenburgh},
  journal={Journal of cellular physiology},
  year={1983},
  volume={116 3},
  pages={363-71}
}
Passive stretch (10-12%) of tissue-cultured avian skeletal myotubes in serum-containing medium stimulates myotube growth in a manner analogous to hormonal stimulation of adult muscle. The resulting increase in myotube length is accompanied by marked reduction in the number of surface microvilli seen by scanning electron microscopy. We investigated the possible involvement of exogenous growth factors in the transduction of stretch-induced alterations in cell shape into the concurring biochemical… CONTINUE READING
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