Cell shape and division in Escherichia coli: experiments with shape and division mutants.

@article{Begg1985CellSA,
  title={Cell shape and division in Escherichia coli: experiments with shape and division mutants.},
  author={Kenneth J. Begg and William D. Donachie},
  journal={Journal of bacteriology},
  year={1985},
  volume={163 2},
  pages={615-22}
}
Double mutants which carry mutations in genes (rodA, pbpA) required for cell elongation (i.e., maintenance of rod shape) in combination with mutations in genes (ftsA, ftsI, ftsQ, or ftsZ) required for septation were constructed. Such mutants were able to grow for about two mass doublings at a normal rate at the restrictive temperature (42 degrees C). The morphology of the cells formed under these conditions was interpreted by assuming the existence of a generalized system for peptidoglycan… CONTINUE READING