Cell resolved, multiparticle model of plastic tissue deformations and morphogenesis

  title={Cell resolved, multiparticle model of plastic tissue deformations and morphogenesis},
  author={Andr{\'a}s Czir{\'o}k and Dona G. Isai},
  journal={Physical Biology},
We propose a three-dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue plasticity is modeled by a stochastic process consisting of a connectivity change (addition or removal of a single link) followed by a complete relaxation to mechanical equilibrium. In particular, we assume that (i) two non-connected, but adjacent particles can form… 

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