Cell replacement therapy for central nervous system diseases

  title={Cell replacement therapy for central nervous system diseases},
  author={Danju Tso and Randall D Mckinnon},
  booktitle={Neural regeneration research},
The brain and spinal cord can not replace neurons or supporting glia that are lost through traumatic injury or disease. In pre-clinical studies, however, neural stem and progenitor cell transplants can promote functional recovery. Thus the central nervous system is repair competent but lacks endogenous stem cell resources. To make transplants clinically feasible, this field needs a source of histocompatible, ethically acceptable and non-tumorgenic cells. One strategy to generate patient… CONTINUE READING