Cell-protection mechanism through autophagy in HGFs/S. mitis co-culture treated with Chitlac-nAg.

@article{Gallorini2016CellprotectionMT,
  title={Cell-protection mechanism through autophagy in HGFs/S. mitis co-culture treated with Chitlac-nAg.},
  author={Marialucia Gallorini and Viviana di Giacomo and Valentina Di Valerio and Monica Rapino and Domenico Bosco and Andrea Travan and Mara di Giulio and Roberta Di Pietro and Sergio Paoletti and Amelia Cataldi and Silvia Sancilio},
  journal={Journal of materials science. Materials in medicine},
  year={2016},
  volume={27 12},
  pages={186}
}
Silver-based products have been proven to be effective in retarding and preventing bacterial growth since ancient times. In the field of restorative dentistry, the use of silver ions/nanoparticles has been explored to counteract bacterial infections, as silver can destroy bacterial cell walls by reacting with membrane proteins. However, it is also cytotoxic towards eukaryotic cells, which are capable of internalizing nanoparticles. In this work, we investigated the biological effects of Chitlac… CONTINUE READING