Cell proliferation studies in primary synovial chondromatosis.

  title={Cell proliferation studies in primary synovial chondromatosis.},
  author={Richard A. Davis and Heather Foster and Keith Arthur and S. Trewin and Peter William Hamilton and D J Biggart},
  journal={The Journal of pathology},
  volume={184 1},
Primary synovial chondromatosis (PSC) is thought to be a cartilaginous metaplasia, but it may recur locally and malignant change has been reported. Histologically, the cartilage is usually cellular, with binucleate forms. These findings suggest that the disease is not simply a metaplasia but imply a proliferative component. In this study, immunohistochemical detection of Ki-67 protein using an antigen retrieval microwave heating technique and DNA image cytometry (VIDAS image analysis system… CONTINUE READING
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