Cell proliferation kinetics and genotoxicity in lymphocytes of smokers living in Mexico City.

@article{CaldernEzquerro2007CellPK,
  title={Cell proliferation kinetics and genotoxicity in lymphocytes of smokers living in Mexico City.},
  author={Carmen Calder{\'o}n-Ezquerro and Alberto S{\'a}nchez-Reyes and Ra{\'u}l Humberto Sansores and Rafael Villalobos-Pietrini and Omar Amador-Mu{\~n}{\'o}z and C Guerrero-Guerra and Mar{\'i}a Elena Calder{\'o}n-Segura and Ra{\'u}l Uribe-Hern{\'a}ndez and Sandra G{\'o}mez-Arroyo},
  journal={Human & experimental toxicology},
  year={2007},
  volume={26 9},
  pages={715-22}
}
Genotoxicity caused by tobacco smoke was assessed in peripheral blood lymphocytes of smokers living in Mexico City by determining sister chromatid exchange (SCE), cell proliferation kinetics (CPK), replication index (RI) and mitotic index (MI). Nicotine levels, and its major metabolite cotinine, were also estimated in urine samples using gas-chromatography-mass spectrometry to quantify smoking intensity. The outcome of the analysis and the comparison of the 77-smoker group with a non-smoking… CONTINUE READING