Cell proliferation in mammalian gastrulation: the ventral node and notochord are relatively quiescent.

@article{Bellomo1996CellPI,
  title={Cell proliferation in mammalian gastrulation: the ventral node and notochord are relatively quiescent.},
  author={Domenico Bellomo and Arthur Lander and I Harragan and Nigel Brown},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={1996},
  volume={205 4},
  pages={471-85}
}
During gastrulation, the node of the mammalian embryo appears to be an organising centre, homologous to Hensen's node in the chick and the dorsal lip of the amphibian blastopore. In addition, the node serves as a precursor population for the head process, notochord and foregut endoderm. We have studied node architecture and cell morphology by electron microscopy, and cell proliferation using bromodeoxyuridine incorporation and mitotic counts. The dorsal (ectodermal) and ventral (endodermal… CONTINUE READING

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