Cell proliferation in human soft tissue tumors correlates with platelet-derived growth factor B chain expression: an immunohistochemical and in situ hybridization study.

@article{wang1994CellPI,
  title={Cell proliferation in human soft tissue tumors correlates with platelet-derived growth factor B chain expression: an immunohistochemical and in situ hybridization study.},
  author={Jiang. wang and Marc D. Coltrera and Allen M. Gown},
  journal={Cancer research},
  year={1994},
  volume={54 2},
  pages={560-4}
}
The authors tested the hypothesis that the B chain of the platelet-derived growth factor (PDGF), a known connective tissue mitogen and growth factor, could be expressed by human soft tissue tumors, and that its expression could play a role in the control of cell proliferation in these tumors. Using a set of 56 soft tissue tumors, including benign tumors and all three grades of sarcomas, PDGF-B chain protein was localized using immunohistochemistry and PDGF-B mRNA was localized using in situ… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Current Molecular Targeted Therapies for Bone and Soft Tissue Sarcomas

International journal of molecular sciences • 2018
View 1 Excerpt

Pazopanib, a new therapy for metastatic soft tissue sarcoma.

Expert opinion on pharmacotherapy • 2013
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Advances in flow cytometry for diagnostic pathology.

Laboratory investigation; a journal of technical methods and pathology • 1994
View 1 Excerpt

Principles of cell proliferation: cell kinetics

I F.Tannock
Research. on October • 1994

Clinical application of morphologic and immunocytochemical assessments of cell proliferation

M. D. Linden, Torres, X E, J. Kubus, R. J. Zarbo
Am. J. Clin. Pathol., • 1992
View 1 Excerpt

Similar Papers

Loading similar papers…