Cell proliferation and death: forgotten features of chronic lymphocytic leukemia B cells.

@article{Chiorazzi2007CellPA,
  title={Cell proliferation and death: forgotten features of chronic lymphocytic leukemia B cells.},
  author={Nicholas Chiorazzi},
  journal={Best practice & research. Clinical haematology},
  year={2007},
  volume={20 3},
  pages={399-413}
}
Chronic lymphocytic leukemia (CLL) results from an accumulation of abnormal B cells due to an imbalance between birth and death rates such that the former exceeds the latter. This imbalance can occur as a result of increased birth, decreased death, or a combination of the two. CLL has long been considered a disease in which cell accumulation results from decreased death, due to a genetic defect, with minimal birth of the leukemic clone. This view was promulgated when experimental options were… CONTINUE READING
55 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 55 extracted citations

Similar Papers

Loading similar papers…