Cell proliferation and cytoarchitectural remodeling during spinal cord reconnection in the fresh-water turtle Trachemys dorbignyi

@article{Rehermann2011CellPA,
  title={Cell proliferation and cytoarchitectural remodeling during spinal cord reconnection in the fresh-water turtle Trachemys dorbignyi},
  author={Mar{\'i}a In{\'e}s Rehermann and Federico Fernando Santi{\~n}aque and Beatriz L{\'o}pez-Carro and Ra{\'u}l E. Russo and Omar Trujillo-Cen{\'o}z},
  journal={Cell and Tissue Research},
  year={2011},
  volume={344},
  pages={415-433}
}
In fresh-water turtles, the bridge connecting the proximal and caudal stumps of transected spinal cords consists of regenerating axons running through a glial cellular matrix. To understand the process leading to the generation of the scaffold bridging the lesion, we analyzed the mitotic activity triggered by spinal injury in animals maintained alive for 20–30 days after spinal cord transection. Flow cytometry and bromodeoxyuridine (BrdU)-labeling experiments revealed a significant increment of… CONTINUE READING