Cell proliferation, apoptosis and apoptosis-related factors in odontogenic keratocysts and in dentigerous cysts.

@article{Kichi2005CellPA,
  title={Cell proliferation, apoptosis and apoptosis-related factors in odontogenic keratocysts and in dentigerous cysts.},
  author={Eisuke Kichi and Yasunobu Enokiya and Takashi Muramatsu and Sadamitsu Hashimoto and Takashi Inoue and Yoshihiro Abiko and Masaki Shimono},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2005},
  volume={34 5},
  pages={280-6}
}
BACKGROUND The purpose of this study was to elucidate why odontogenic keratocysts (OKC) can form cystic lesions but not tumor masses, notwithstanding their prominent proliferative activity. METHODS We investigated cellular proliferation, cell death, and expression of apoptosis-related proteins in the lining cells of OKCs and of dentigerous cysts (DGCs). RESULTS TdT-mediated dUTP-biotin nick end labeling (TUNEL)-positive cells were observed in the surface layers of OKCs and of DGCs. However… CONTINUE READING

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