Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function.

@article{Willemsen2003CellPA,
  title={Cell polarity and PIN protein positioning in Arabidopsis require STEROL METHYLTRANSFERASE1 function.},
  author={Viola Willemsen and Jiř{\'i} Friml and Markus Grebe and Albert van den Toorn and Klaus Palme and Ben Scheres},
  journal={The Plant cell},
  year={2003},
  volume={15 3},
  pages={
          612-25
        }
}
Plants have many polarized cell types, but relatively little is known about the mechanisms that establish polarity. The orc mutant was identified originally by defects in root patterning, and positional cloning revealed that the affected gene encodes STEROL METHYLTRANSFERASE1, which is required for the appropriate synthesis and composition of major membrane sterols. smt1(orc) mutants displayed several conspicuous cell polarity defects. Columella root cap cells revealed perturbed polar… CONTINUE READING

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