Cell polarity: Sticky poles

  title={Cell polarity: Sticky poles},
  author={Arianne Heinrichs},
  journal={Nature Reviews Molecular Cell Biology},
  • A. Heinrichs
  • Published 15 October 2008
  • Biology
  • Nature Reviews Molecular Cell Biology
A N D X During bacterial cell division, replicated chromosome origins are targeted to opposite cell poles. This is required for accurate chromosome segregation and cell division. But how chromosome origins are localized to and retained at cell poles is poorly understood. The groups of Shapiro and Jacobs-Wagner have now identified PopZ, a multimeric protein in Caulobacter crescentus that anchors chromosome origins at bacterial cell poles. Both groups identified the popZ gene in a screen for…