Cell-penetrating peptides split into two groups based on modulation of intracellular calcium concentration.

Abstract

Cell-penetrating peptides (CPPs) promote the uptake of different cargo molecules, e.g. therapeutic compounds, making the harnessing of CPPs a promising strategy for drug design and delivery. However, the internalization mechanisms of CPPs are still under discussion, and it is not clear how cells compensate the disturbances induced by peptides in the plasma… (More)
DOI: 10.1074/jbc.M111.318063

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