Cell penetrating peptides. How do they get through membranes?

Abstract

In 1988 it was discovered, that a natural polycationic protein, the trans-acting activator of transcription (TAT) of the human immunodeficiency virus (HIV-1), passed very efficiently through cell membranes of cultured mammalian cells. Covalently binding the TAT protein (or a specific peptide sequence of it) to proteins or fluorescent markers allowed these… (More)

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Cite this paper

@inproceedings{SeeligCellPP, title={Cell penetrating peptides. How do they get through membranes?}, author={Joachim Seelig and Li Blatter and Pierluigi Nervi} }