Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma: the role of gelsolin expression.

@article{Shieh1999CellMA,
  title={Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma: the role of gelsolin expression.},
  author={Dar Bin Shieh and John Godleski and James E. Herndon and Takeshi Azuma and Heather Mercer and David J. Sugarbaker and David J Kwiatkowski},
  journal={Cancer},
  year={1999},
  volume={85 1},
  pages={47-57}
}
BACKGROUND Tumor cell motility is an important characteristic that facilitates the multistep process of tumor metastasis. Rac, ABP-280, and gelsolin are proteins that interact with actin and are important in cell motility. METHODS The authors studied a cohort of 229 Stage I nonsmall cell lung carcinoma (NSCLC) patients who had a minimum of 3 years follow-up and had been previously analyzed for 22 clinical, pathologic, and molecular features, of which 9 had been found to provide significant… CONTINUE READING

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