Cell micropatterning reveals the modulatory effect of cell shape on proliferation through intracellular calcium transients.

Abstract

The mechanism by which cell shape regulates the function of the cell is one of the most important biological issues, but it remains unclear. Here, we investigated the effect of the regulation of cell shape on proliferation by using a micropatterning approach to confine MC3T3-E1 cells into specific shapes. Our results show that the proliferation rate for… (More)
DOI: 10.1016/j.bbamcr.2017.09.015

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