Cell membranes impermeable to NH3

@article{Kikeri1989CellMI,
  title={Cell membranes impermeable to NH3},
  author={Deepak Kikeri and Adam Sun and Mark Lawrence Zeidel and Steven C. Hebert},
  journal={Nature},
  year={1989},
  volume={339},
  pages={478-480}
}
CLASSICALLY, there is a direct correlation between the lipophilic nature of a molecule and its rate of permeation across a biological membrane,1,2 so cell membranes should be more permeable to small, neutral molecules than they are to charged molecular species of similar size. Consequently, the distribution of NH4+ in biological systems is generally… CONTINUE READING