Cell membrane receptors for polypeptide hormones. Application to the study of disease states in mice, and men.

Abstract

Recent studies have suggested that the first step in the action of polypeptide hormones and catecholamines is binding to surface membrane receptor sites. This interaction can be studied directly using radioactively labeled hormones and a variety of receptor preparations. With these radioreceptor assay technics, it has been possible to define structure… (More)

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