Cell-mediated immunity to Pityrosporum orbiculare in tinea versicolor.

  title={Cell-mediated immunity to Pityrosporum orbiculare in tinea versicolor.},
  author={Peter G. Sohnle and C Collins-Lech},
  journal={The Journal of clinical investigation},
  volume={62 1},
Pityrosporum orbiculare, the presumed etiologic agent of tinea versicolor, was cultured in vitro and antigenic extracts prepared from the cultured organisms. Studies with lymphocytes from human cord blood and peripheral blood of guinea pigs demonstrated that such extracts were not mitogenic. Further studies in guinea pigs indicated that the animals could be sensitized by the injection of P. orbiculare extract in Freund's complete adjuvant and that this extract could elicit lymphocyte… CONTINUE READING