Cell-mediated immunity in experimental parainfluenza type 3 virus infection.

@article{Ramakrishnan1980CellmediatedII,
  title={Cell-mediated immunity in experimental parainfluenza type 3 virus infection.},
  author={I Ramakrishnan and Saveta Choraria Agarwal},
  journal={Journal of medical microbiology},
  year={1980},
  volume={13 4},
  pages={
          527-34
        }
}
Local respiratory-tract infection was produced experimentally in guinea-pigs by intranasal instillation of a suspension of parainfluenza virus type 3. Histologically, interstitial pneumonitis developed within 10 days and persisted for at least 70 days. Cell-mediated immunity was measured at intervals for 70 days after infection. Dermal reactivity could not be elicited. Leucocyte-migration inhibition and macrophage-migration inhibition were increased. Macrophage aggregation was present… 
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2 Citations

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Isolation of a Parainfluenza Virus Type 3-like Agent from Guinea Pigs
TLDR
This is the first report of the isolation of a type 3-like parainfluenza virus from GP, and this finding is significant, in-sofar as an inapparent infection with the virus may con-cern animal experimentation in the use of GP.
Potential targets for host defence modulation

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