Cell mediated immune response after challenge in Omp25 liposome immunized mice contributes to protection against virulent Brucella abortus 544.

@article{Goel2013CellMI,
  title={Cell mediated immune response after challenge in Omp25 liposome immunized mice contributes to protection against virulent Brucella abortus 544.},
  author={Divya Goel and Vinoth Rajendran and Prahlad Chandra Ghosh and Rakesh Bhatnagar},
  journal={Vaccine},
  year={2013},
  volume={31 8},
  pages={
          1231-7
        }
}
Brucellosis is a disease affecting various domestic and wild life species, and is caused by a bacterium Brucella. Keeping in view the serious economic and medical consequences of brucellosis, efforts have been made to prevent the infection through the use of vaccines. Cell-mediated immune responses [CMI] involving interferon gamma and cytotoxic CD4(+) and CD8(+) T cells are required for removal of intracellular Brucella. Omp25 has been reported to be involved in virulence of Brucella melitensis… CONTINUE READING
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