Cell-mediated cytotoxicity in relation to active immunotherapy in acute myeloid leukaemia

Abstract

Tests comparing lymphocytes from normal controls, remission AML patients not receiving immunotherapy, and AML immunotherapy patients showed that cell-mediated cytotoxicity (CMC) to allogeneic AML cells requires in vivo priming and in vitro stimulation by AML cells. An in vitro lymphoproliferative response to allogeneic AML cells correlated with the… (More)
DOI: 10.1007/BF00200150

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