Cell lines derived from mouse neural crest are representative of cells at various stages of differentiation.

@article{Murphy1991CellLD,
  title={Cell lines derived from mouse neural crest are representative of cells at various stages of differentiation.},
  author={Maria A. Murphy and Ora Bernard and Kate Emily Reid and Perry F. Bartlett},
  journal={Journal of neurobiology},
  year={1991},
  volume={22 5},
  pages={522-35}
}
In order to study mammalian neural crest differentiation in vitro, a series of clonal neural crest (NC) cell lines have been generated by infection of migrating mouse neural crest cells with two recombinant retroviruses containing either the c-myc or N-myc proto-oncogenes. Many cell lines were generated which could be subdivided into three groups based on their appearance in culture. Eleven of these cell lines representative of each of the morphological groups were characterized for the… CONTINUE READING