Cell lineage specificity of expression of the murine transforming growth factor beta 3 and transforming growth factor beta 1 genes.

@article{Watrin1991CellLS,
  title={Cell lineage specificity of expression of the murine transforming growth factor beta 3 and transforming growth factor beta 1 genes.},
  author={Françoise Watrin and Luigi Scotto and Richard K. Assoian and Debra J. Wolgemuth},
  journal={Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research},
  year={1991},
  volume={2 2},
  pages={77-83}
}
We have cloned a murine transforming growth factor (TGF) beta 3 complementary (cDNA) from normal tissue by low stringency screening of a testicular cDNA library with a TGF beta 1 probe. The coding domain of this TGF beta 3 cDNA agrees completely with the sequence reported for the TGF beta 3 cDNA isolated from the AKR-2B cell line, but the testicular clone uses a distinct and unusual polyadenylation signal resulting in an altered 3' untranslated domain. Northern blot hybridization analysis of… CONTINUE READING