Cell kinetic balance in gastric mucosa with intestinal metaplasia after Helicobacter pylori eradication: 2-year follow-up study.

@article{Wambura2004CellKB,
  title={Cell kinetic balance in gastric mucosa with intestinal metaplasia after Helicobacter pylori eradication: 2-year follow-up study.},
  author={Casmir Marwa Wambura and Nobuo Aoyama and Daisuke Shirasaka and Kohei Kuroda and Yoshinori Watanabe and Ikuya Miki and Takao Tamura and Masato Kasuga},
  journal={Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver},
  year={2004},
  volume={36 3},
  pages={178-86}
}
BACKGROUND Proliferation and apoptosis events are altered in Helicobacter pylori infection. However, whether H. pylori eradication has an effect on the disturbed kinetics in metaplastic mucosa has not been well elucidated. AIM To investigate the effect of eradication on the gastric cell kinetics. SUBJECTS AND METHODS Initially, biopsies were obtained from 74 H. pylori-infected subjects and repeated 12 and 24 months after eradication. Biopsies were immunohistochemically stained for apoptosis… CONTINUE READING