Cell kinetic analyses of human malignant brain tumors (gliomas).

@article{Hoshino1979CellKA,
  title={Cell kinetic analyses of human malignant brain tumors (gliomas).},
  author={Takao Hoshino and Charles Bo Wilson},
  journal={Cancer},
  year={1979},
  volume={44 3},
  pages={
          956-62
        }
}
Administration of 3H-thymidine, either with or without mitostatic agents, to 24 patients with various gliomas revealed 1) in viable areas a labeling index (LI) for glioblastomas equal to 5-15%, 2) an LI of 1% or less in well-differentiated gliomas, and 3) the LI of anaplastic astrocytomas was intermediate and reflected the extent of anaplasia. Growth fraction was 0.14-0.44 in malignant gliomas (average 0.31 +/- 0.10), and cell cycle time obtained by means of stathmokinetic analysis was 75.6… CONTINUE READING
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