Cell fusion as a hidden force in tumor progression.

  title={Cell fusion as a hidden force in tumor progression.},
  author={Xin Lu and Yibin Kang},
  journal={Cancer research},
  volume={69 22},
Cell fusion plays an essential role in fertilization, formation of placenta, bone and muscle tissues, immune response, tissue repair, and regeneration. Increasing recognition of cell fusion in somatic cell dynamics has revitalized the century-old hypothesis that cell fusion may contribute to the initiation and progression of cancer. In this review, we discuss findings from experimental and clinical studies that suggest a potentially multifaceted involvement of cell fusion in different stages of… CONTINUE READING
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