Cell-free circulating tumor DNA in cancer.

  title={Cell-free circulating tumor DNA in cancer.},
  author={Zhen Qin and Vladimir A Ljubimov and Cuiqi Zhou and Yunguang Tong and Jimin Liang},
  journal={Chinese journal of cancer},
Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in tumor treatment and failure of a number of current therapeutic modalities, even of molecularly targeted therapies. The development of a virtually noninvasive "liquid biopsy" from the blood has been attempted to characterize tumor heterogeneity… CONTINUE READING
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