Cell-free DNA in urine: a marker for kidney graft rejection, but not for prenatal diagnosis?

@article{Zhong2001CellfreeDI,
  title={Cell-free DNA in urine: a marker for kidney graft rejection, but not for prenatal diagnosis?},
  author={X. Y. Zhong and Deirdre Hahn and Carolyn Troeger and Anke Klemm and Guenter Stein and Pippa A Thomson and Wolfgang Holzgreve and Sinuhe Hahn},
  journal={Annals of the New York Academy of Sciences},
  year={2001},
  volume={945},
  pages={250-7}
}
Intrigued by the rapid clearance of free fetal DNA from the maternal circulation, we have investigated whether this fetal genetic material could be cleared via the kidney. For this purpose, we examined for the presence of Y chromosome-specific DNA sequences in urine samples obtained from 8 women pregnant with male fetuses. No male-specific sequences could… CONTINUE READING