Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells

@article{Ma2008CellextracellularMI,
  title={Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells},
  author={Wu Ma and Tahereh Tavakoli and Eric Derby and Yevgeniya Serebryakova and Mahendra S. Rao and Mark P. Mattson},
  journal={BMC Developmental Biology},
  year={2008},
  volume={8},
  pages={90 - 90}
}
Interactions of cells with the extracellular matrix (ECM) are critical for the establishment and maintenance of stem cell self-renewal and differentiation. However, the ECM is a complex mixture of matrix molecules; little is known about the role of ECM components in human embryonic stem cell (hESC) differentiation into neural progenitors and neurons. A reproducible protocol was used to generate highly homogenous neural progenitors or a mixed population of neural progenitors and neurons from… CONTINUE READING
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