Cell expression of GDAP1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease

@inproceedings{Pedrola2008CellEO,
  title={Cell expression of GDAP1 in the nervous system and pathogenesis of Charcot-Marie-Tooth type 4A disease},
  author={Laia Pedrola and Antonio Espert and Teresa Vald{\'e}s-S{\'a}nchez and Maribel S{\'a}nchez-Piris and Erich E Sirkowski and Steven S. Scherer and Isabel Fari{\~n}as and Francesc Palau},
  booktitle={Journal of cellular and molecular medicine},
  year={2008}
}
Mutations in the mitochondrial protein GDAP1 are the cause of Charcot-Marie-Tooth type 4A disease (CMT4A), a severe form of peripheral neuropathy associated with either demyelinating, axonal or intermediate phenotypes. GDAP1 is located in the outer mitochondrial membrane and it seems that may be related with the mitochondrial network dynamics. We are… CONTINUE READING