Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor.

Abstract

Several cell surface molecules have been proposed as receptor candidates, mediating cell entry of hepatitis C virus (HCV) on the basis of their physical association with virions or with soluble HCV E2 glycoproteins. However, due to the lack of infectious HCV particles, evidence that these receptor candidates support infection was missing. Using our recently… (More)

Topics

Cite this paper

@article{Bartosch2003CellEO, title={Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor.}, author={Birke Bartosch and Alessandra Vitelli and Christelle Granier and C. P. Goujon and Jean Dubuisson and Simona Pascale and Elisa Scarselli and R. Cortese and Alfredo Nicosia and François-Lo{\"i}c Cosset}, journal={The Journal of biological chemistry}, year={2003}, volume={278 43}, pages={41624-30} }