Cell division orientation on biospecific peptide gradients.

@article{Lamb2014CellDO,
  title={Cell division orientation on biospecific peptide gradients.},
  author={Brian Matthew Lamb and Wei Luo and Sarbajeet Nagdas and Muhammad N Yousaf},
  journal={ACS applied materials & interfaces},
  year={2014},
  volume={6 14},
  pages={
          11523-8
        }
}
An assay was developed for determining cell division orientation on gradients. The methodology is based on permeating microfluidic devices with alkanethiols and subsequent printing of cell adhesive peptide gradient self-assembled monolayers (SAMs) for examining oriented cell divisions. To our knowledge, there has been no study examining the correlation between cell division orientations based on an underlying ligand gradient. These results implicate an important role for how the extracellular… CONTINUE READING
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