Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies.

@article{Watanabe1992CellDA,
  title={Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies.},
  author={Takeshi Watanabe and Yasuko Ono and Yoshihiro Taniyama and Kenji Hazama and Kazuei Igarashi and Kazuhide Ogita and Ushio Kikkawa and Yasutomi Nishizuka},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 21},
  pages={10159-63}
}
Several lines of CHO cells stably overexpressing protein kinase C (PKC) subspecies to various extents were established by the DNA-mediated transfer. Upon treatment with phorbol 12-myristate 13-acetate, the growth of the cells expressing the PKC-delta subspecies was markedly inhibited, whereas cell lines expressing PKC-alpha, PKC-beta II, and PKC-zeta… CONTINUE READING