Cell distribution of stress fibres in response to the geometry of the adhesive environment.

@article{Thry2006CellDO,
  title={Cell distribution of stress fibres in response to the geometry of the adhesive environment.},
  author={Manuel Th{\'e}ry and Anne Sophie Pepin and Emilie Dressaire and Yong Gang Chen and Michel Bornens},
  journal={Cell motility and the cytoskeleton},
  year={2006},
  volume={63 6},
  pages={
          341-55
        }
}
Cells display a large variety of shapes when plated in classical culture conditions despite their belonging to a common cell type. These shapes are transitory, since cells permanently disassemble and reassemble their cytoskeleton while moving. Adhesive micropatterns are commonly used to confine cell shape within a given geometry. In addition the micropattern can be designed so as to impose cells to spread upon adhesive and nonadhesive areas. Modulation of the pattern geometry allows the… CONTINUE READING
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