Cell differentiation and the development of colonic neoplasms

@article{Lipkin1970CellDA,
  title={Cell differentiation and the development of colonic neoplasms},
  author={Martin Lipkin and Eleanor E. Deschner and Frank J. Troncale},
  journal={CA: A Cancer Journal for Clinicians},
  year={1970},
  volume={20}
}
develop cancer of the colon and rectum. These lesions are now responsible for a greater number of cancer deaths than any other single organ site with the exception of lung. Annual mortality rates of colon and rectal cancer are higher in the United States than in many other countries with differences partly due to different age distributions of the populations. However, similar ethnic groups living in geographic areas adjacent to one another also develop differences in frequency and immigrant… 

Changes in composition of mucin in the mucosa adjacent to carcinoma of the colon as compared with the normal: A biochemical investigation

TLDR
It is suggested that the changes described in the transitional mucosa are transformations representing an early stage of carcinogenesis.

Polypoid lesions of the colon. Which should be removed?

  • G. Behringer
  • Medicine
    The Surgical clinics of North America
  • 1974

Chromosomal banding patterns in human large bowel adenomas

TLDR
Chromosome studies were performed on direct preparations of 38 benign human large bowel adenomas by fluorescent banding techniques, finding the most common finding was trisomy of 7, 8, or 13.

Sialic acids of human large bowel mucosa: o-acylated variants in normal and malignant states.

TLDR
Five sialic acid variants have been demonstrated in normal, 'transitional', and tumour extracts of human large bowel mucosa by thin-layer chromatography, and it was confirmed that the variants were N-acetyl neuraminic acids with additional O-acylation.

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