Cell determination boundaries as organizing regions for secondary embryonic fields.

@article{Meinhardt1983CellDB,
  title={Cell determination boundaries as organizing regions for secondary embryonic fields.},
  author={Hans Meinhardt},
  journal={Developmental biology},
  year={1983},
  volume={96 2},
  pages={375-85}
}
A model is proposed for pattern formation in secondary embryonic fields. It is stipulated that the boundaries, resulting from the primary embryonic organization of a developing organism, act as organizing regions for secondary embryonic fields, e.g., imaginal discs in insects. This boundary mechanism would allow very reliable pattern formation in the course of development: Primary positional information leads to cells of different determination, separated by sharp borders. At these borders, in… CONTINUE READING