Cell-derived microparticles: a new challenge in neuroscience.

@article{Doeuvre2009CellderivedMA,
  title={Cell-derived microparticles: a new challenge in neuroscience.},
  author={Lo{\"i}c Doeuvre and Laurent Plawinski and Florence Toti and Eduardo Angl{\'e}s-Cano},
  journal={Journal of neurochemistry},
  year={2009},
  volume={110 2},
  pages={
          457-68
        }
}
Microparticles (MPs) are membrane fragments shed by cells activated by a variety of stimuli including serine proteases, inflammatory cytokines, growth factors, and stress inducers. MPs originating from platelets, leukocytes, endothelial cells, and erythrocytes are found in circulating blood at relative concentrations determined by the pathophysiological context. The procoagulant activity of MPs is their most characterized property as a determinant of thrombosis in various vascular and systemic… CONTINUE READING

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