Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth

@inproceedings{Cantelmo2010CellDO,
  title={Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth},
  author={Anna Rita Cantelmo and Rosaria Cammarota and Douglas M Noonan and Chiara Focaccetti and Paolo Maria Comoglio and Maria Prat and Adriana Albini},
  booktitle={Oncogene},
  year={2010}
}
Hepatocyte growth factor (HGF) and its receptor Met are responsible for a wide variety of cellular responses, both physiologically during embryo development and tissue homeostasis, and pathologically, particularly during tumor growth and dissemination. In cancer, Met can act as an oncogene on tumor cells, as well as a pro-angiogenic factor activating endothelial cells and inducing new vessel formation. Molecules interfering with Met activity could be valuable therapeutic agents. Here we have… CONTINUE READING

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