Cell death pathway induced by resveratrol-bovine serum albumin nanoparticles in a human ovarian cell line

@inproceedings{Guo2015CellDP,
  title={Cell death pathway induced by resveratrol-bovine serum albumin nanoparticles in a human ovarian cell line},
  author={Liyuan Guo and Yan Peng and Yulian Li and Jingping Yao and Guangmei Zhang and Jian Chen and Jing Wang and Lihua Sui},
  booktitle={Oncology letters},
  year={2015}
}
Resveratrol-bovine serum albumin nanoparticles (RES-BSANP) exhibit chemotherapeutic properties, which trigger apoptosis. The aim of the present study was to investigate the caspase-independent cell death pathway induced by RES-BSANP in human ovarian cancer SKOV3 cells and to analyze its mechanism. Morphological changes were observed by apoptotic body/cell nucleus DNA staining using inverted and fluorescence microscopy. The cell death pathway was determined by phosphatidylserine translocation… CONTINUE READING