Cell death is induced by ciglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist, independently of PPARγ in human glioma cells.

Abstract

Peroxisome proliferator-activated receptor γ (PPARγ) regulates multiple signaling pathways, and its agonists induce apoptosis in various cancer cells. However, their role in cell death is unclear. In this study, the relationship between ciglitazone (CGZ) and PPARγ in CGZ-induced cell death was examined. At concentrations of greater than 30 μM, CGZ, a… (More)
DOI: 10.1016/j.bbrc.2011.12.001

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@article{Lee2012CellDI, title={Cell death is induced by ciglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist, independently of PPARγ in human glioma cells.}, author={Myoung Woo Lee and Dae Seong Kim and Hye Ryung Kim and Hye Jin Kim and Jin Mo Yang and Somi Ryu and Yoo Hun Noh and Soo Hyun Lee and Meong Hi Son and Hye Lim Jung and Keon Hee Yoo and Hong Hoe Koo and Ki Woong Sung}, journal={Biochemical and biophysical research communications}, year={2012}, volume={417 1}, pages={552-7} }