Cell death in the skin

@article{Lippens2009CellDI,
  title={Cell death in the skin},
  author={Saskia Lippens and Esther Hoste and Peter Vandenabeele and Patrizia Agostinis and Wim Declercq},
  journal={Apoptosis},
  year={2009},
  volume={14},
  pages={549-569}
}
The skin is the largest organ of the body and protects the organism against external physical, chemical and biological insults, such as wounding, ultraviolet radiation and micro-organisms. The epidermis is the upper part of the skin that is continuously renewed. The keratinocytes are the major cell type in the epidermis and undergo a specialized form of programmed cell death, called cornification, which is different from classical apoptosis. In keep with this view, several lines of evidence… 
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