Cell death in the mosaic epididymis of sex reversed mice, heterozygous for testicular feminization

@article{Drews2004CellDI,
  title={Cell death in the mosaic epididymis of sex reversed mice, heterozygous for testicular feminization},
  author={U. Drews and H. J. Dieterich},
  journal={Anatomy and Embryology},
  year={2004},
  volume={152},
  pages={193-203}
}
SummarySex reversed mice heterozygous for testicular feminization are genetic females which are converted to males by the autosomal Sxr (“sex reversed”) mutation, thus imitating the Y-chromosome. They carry on one of their X-chromosomes the mutation for testicular feminization. Then, X-inactivation leads to the formation of a mosaic of androgen insensitive Xtfm and androgen sensitive X+ cells. In the epididymis the Tfm cells are maintained into adulthood as undifferentiated flat cells. There… Expand
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